The Top 5 Cannabinoids
#1 THC or Delta(9)-tetrahydrocannabinol
The most famous cannabinoid is the compound responsible for giving the "high" feeling, and is what has given cannabis it's bad reputation. Things are changing slowly for THC through medical research and through states choosing to legalize the substance for medical and recreational use.
#2 CBD or Cannabidiol
With the discovery of the Endocannabinoid System 25 years ago and its role as the bodies master regulator, Cannabidiol (CBD) a cannabinoid derived from the hemp plant has proven to be a key molecule in regulating this system. Cannabidiol is non-psycoactive. How cannabidiol works is still being sorted out by scientists. It produces many beneficial effects through multiple pathways. Although cannabidiol does not bind directly with CB1 & CB2 receptors, it activates several non cannabinoid receptors and ion channels which in turn help regulate physiological functions throughout our body. Terpenes also aid in this process. While we cannot make medical claims, Full Spectrum CBD Rich Hemp medicines are often recommended by progressive physicians in the treatment of nerve damage, psychosis, inflammatory conditions, AIDS, chronic pain, diabetes, epilepsy, cancer, depression, anxiety, bipolar disorder, bone disease and age related disorders such as alzheimers and dementia, among others.
#3 CBC or Cannabichromene
CBC is the third most common cannabinoid which has been shown to be effective in certain treatments on its own but becomes more effective when paired with other cannabinoids. Like CBD, it is non-psychoactive and won't produce the "high" commonly associated with cannabis use. While we cannot make medical claims, research has shown it is useful in anti-inflammatory, anti-depressive, and anti-fungal treatments.
#4 CBN or Cannabinol
As an appetite stimulant, CBN was found to be superior to THC and CBD in animal studies. While we cannot make medical claims, CBN has been shown effective for antibiotic treatment, ALS, anti-asthmatic, sedative, glaucoma, appetite stimulant, and as a pain killer.
#5 CBG or Cannabigerol
This cannabinoid forms early in the Cannabis plant growth cycle. It is usually not very abundant and is non-psychoactive. CBG is especially an effective antimicrobial agent. While we cannot make medical claims, CBG has also been shown effective as an antibiotic, for skin/psoriasis treatment, pain relief, anti-tumor, antidepressant, tranquilizer, and as an anti-psychotic.
The Endo-Cannabinoid System
The human body actually produces its own "endogenous" cannabinoids (chemicals otherwise unique to the cannabis plant). These cannabinoids whether formed in your body or produced in the cannabis plant and consumed or applied topically fit neatly into a series of specialized receptors located throughout the human body and skin cells, with their greatest concentration in the hippocampus (which regulates memory), the cerebral cortex (cognition), the cerebellum (motor coordination), the basal ganglia (movement), the hypothalamus (appetite), and the amygdala (emotions). Cannabinoid receptors are similarly found in "every animal species down to the sponge," Dr. Donald Abrams, chief of hematology / oncology at San Francisco General Hospital.
First identified in 1992, the endocannabinoid system (ECS) consists of CB1 receptors predominantly located in the central and peripheral nervous system, connective tissues, gonads, glands, and organs; and CB2 receptors, primarily found in the immune system and also present in the spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands, and reproductive organs. These receptors are produced by the (ECS) and are stimulated and modulated by compounds called endocannabinoids that are produced naturally in the body, like anandamide (ananda is the Sanskrit word for bliss); or by ingesting botanically-based phytocannabinoids rich in Cannabidiol (CBD), the cannabis plant's best known non-psychoactive compound; or by ingesting synthetic cannabinoids produced in a laboratory. After binding to receptors in the body these endo, phyto, and synthetic cannabinoids all produce a wide range of physiological effects, altering everything from blood pressure to pain response to memory retention to appetite and even to mood elevation, but most importantly for its anti inflamatory and neuro-protective qualities , along with stimulating new nerve growth. Although cannabidiol does not directly bind with these receptors, it functions as a mediator, along with naturally occurring terpenes creating the entourage effect to aid in bringing beneficial physiological balance within the body. Think of cannabinoids as a support element along with proper diet, excercise, sleep, relaxation and spiritual well being.
"The endogenous cannabinoid system, named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health," Dr. Dustin Sulak, a leading practitioner of what some have dubbed cannabinopathic medicine, said during a lecture at the 2010 NORML convention. "In each tissue, the cannabinoid system performs different tasks," he said. "But the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment."
Think of the (ECS) system as your body's "core" operating system - a kind of central processing unit that regulates and alters the functioning of every system and keeps them in balance. The (ECS) is the master regulator of all internal systems and is involved in internal processes down to the cellular and nuclear levels. It not only regulates the production of endocannabinoids and their receptors, it manufactures all of the necessary components needed to facilitate and to breakdown and utilize the cannabinoids. Along with regulating our central nervous system as discussed above, it also regulates the endocrine system which regulates all of our glands as well as our blood. Simply put, the Endocannabinoid System is the most important system in our body and Full Spectrum CBD Rich Hemp Oil is the molecule that brings balance. Take control of your Chemistry!
Terpenes are hydrocarbons that are produced by a wide range of plants. They are aromatic compounds responsible for the pungent odors associated with the hemp plant. Terpenes are what give a rose, lavender, cloves, etc. their distinct smells. Terpenes are used in a wide range of personal care products and scented sprays.
More than 2,000 terpenes exist in nature and the Cannabis Sativa (hemp) plant can produce more than 100 itself.
Terpenes are more than just aromatic compounds though. They are the main building blocks within a plant's physiology that play an important part in the production of plant resins, hormones, vitamins, plant pigments, as well as cannabinoids.
Terpenes comprise 10%-20% of the resin within the trichomes. Trichomes are mushroom shaped heads of resin glands produced by the Cannabis Sativa plant.
Terpenes play an important role in cannabis/hemp medicines. Certain terpenes can regulate how cannabinoids pass through the blood-brain barrier and can alter the rate of production and destruction of serotonin and dopamine neurotransmitters, therefore limiting the movement/availability to cannabinoid receptors.
Terpenes play an incredibly important role by providing us with natural protection from bacteria, fungus, insects, and other environmental stresses.
Most common terpene found in the world
Enhances attention, memory, alertness, and energy
Reduces size of cancerous tumors
Bronchodilator, reduces inflammation in airways and all over the body
Able to cross the blood/brain barrier
Used in treating bacterial and viral infections
Can help alleviate stress, anxiety, and depression
Gastric reflux and digestive aid
Inflammation reducer, modulator within the immune system
Anti-cancer, reduces tumor size and prevents spreading of malignant cells
Can have sedative, relaxing effects
Antiseptic, anti-fungal, and anti-bacterial
Acts as a regulator for other terpenes and cannabinoids, enhancing or buffering their effects
Antioxidant and anti-inflammatory
Can help with insomnia and muscle spasms
Increases bone mass
Blocks pain receptors
Targets CB2 receptors, ignoring CB1 receptors
Helps relieve anxiety and depression
Anti-inflammatory and anti-bacterial
Can help relieve pain
Acts as an appetite suppressant
Has calming, sedative effects
Can help with stress, anxiety, depression, and insomnia
Anti-convulsant - may help with seizures, Parkinson's, and multiple sclerosis
Helpful for chronic pain
Studies suggest it can restore cognitive and emotional functioning (helpful for Alzheimer's Disease)
Significantly reduces lung inflammation